Dementia in Alzheimer's disease - The first warning signs

 

Dementia in Alzheimer's disease

Dementia refers to the appearance of mental symptoms with implications for the social, professional, and intellectual functioning of people who have a process of rapid and irreversible damage to the brain by destroying neurons. This neurodegenerative phenomenon's progression translates into a slower or faster deterioration of functional, cognitive (memory, attention, language, thinking, planning, organization, etc.) and behavioral abilities. There are several forms of dementia, but the most common of these is dementia in Alzheimer's disease, responsible for almost 60% of diagnosed cases. Unfortunately, science has not yet been able to provide effective treatment for this terrible disease, making it all the more important to identify the first signs of the disease as early as possible.

Could it be Alzheimer's disease?

Everyone knows that with age, it is normal to become a bit more "forgetful". Therefore, how can anyone distinguish an embarrassing moment when one of our seniors forgets a detail from the onset of Alzheimer's disease?

It should be noted that about 1 in 8 people over the age of 65 have this devastating form of dementia. In its early stages, the disease can go undiagnosed even by a specialist, let alone friends or family members. However, some alarm signals can lead to the correct and early diagnosis of your disease that we can follow.

WHAT ARE THE ALARM SIGNALS?

1. Memory and speech

In the early stages of the disease, long-term memory of information from the patient's distant past remains unaltered, while short-term information of recent and very recent information may show signs of weakness. The affected person may forget a discussion they had recently, may ask the same thing several times or may have trouble remembering certain words or names.

2. Behavior

In addition to impairing memory and speech, Alzheimer's disease can cause confusion, disorientation, and behavioral changes. The affected person may get lost in well-known places. He may start not taking care of himself, neglecting his hygiene, wearing dirty clothes, not washing his hair. It can present sudden and inexplicable changes of mood, mistakes of judgment.

Most often, frightened by these disturbing states, patients begin to show irritability, a tendency to social isolation, marked anxiety, or even depressive episodes.

DO NOT IGNORE THESE SIGNS!

It is very difficult to face the thought that a dear person, a parent, could have this disease, and denial is the first reaction of most people undergoing this bitter test, but it is much better to consult a psychiatrist sooner rather than later.

First of all, because the diagnosis could be different from what we suspect, it can be the effect of a Major Depressive Episode, endocrinological disorders (e.g., hypothyroidism), metabolic, cardiovascular, or neurological disorders, many of them being treatable if they are correctly and quickly diagnosed. And if there is still dementia in Alzheimer's disease, treatment is most effective in the early stages of the disease.

HOW IS ALZHEIMER'S DISEASE DIAGNOSED?

Until now, there is no single and generally valid method for diagnosing this disease. Therefore, once this suspicion is raised, the psychiatrist you need to see will perform a series of multidisciplinary evaluations to confirm or refute the diagnosis.

Step 1: it is necessary a careful mental examination, which must, with the help of close family members and the patient, determine the degree of damage to the patient from several points of view, compared to the level before the onset of symptoms. Professional, social functioning, attention, memory, thinking, and affectivity are evaluated.

Step 2:  Perform a clinical psychologist's psychological examination, who will determine the degree of cognitive and functional impairment, using clinical scales such as MMSE and GAFS.

Step 3:  consultations that exclude the possibility of having a different cause for the symptoms presented. There will be, if necessary, neurological, endocrinological, cardiological examinations, but also a brain imaging examination, such as computed tomography of the brain or, preferably, a brain MRI. These examinations will bring additional information about the patient's brain, eliminating the risk of having a brain tumor or a stroke.

In some cases, it may be advisable to perform a lumbar puncture to collect a sample of cerebrospinal fluid (CSF) and dose-specific compounds for this disease, called Tau protein and beta-amyloid.

Immediately after confirming the diagnosis and a deeper understanding of the implications of the doctor's information, a series of natural questions arise for those affected. Here are some of the most common:

Q1. What to expect?

R1. The prognosis of Alzheimer's disease is almost impossible to establish from the beginning. In each case, the disease will follow different paths and will generate a variety of problems. Sometimes the symptoms are more focused on the psychic area, other times, they are complicated in the neurological sphere, but it is impossible to know from the beginning. In some cases, there is a rapid and brutal worsening of symptoms, which lead to confusion and severe memory impairment in a few years, regardless of the therapeutic approaches. In other cases, the disease has a slow and predictable evolution, which allows long maintenance of autonomy and patient quality of life. Under these conditions, it can be estimated that this disease can evolve from onset to death between 10 and even 20 years. Unfortunately, statistics show that, from the time of diagnosis,

Q2.  How is the disease treated?

R2. Because so far it has not been possible to obtain a drug treatment that can cure this disease, hope is placed in those treatment schemes that seem to slow the progression of the disease and the mental and social damage affected. The existing treatments' objectives are to maintain as long as possible the autonomy and quality of life of the affected persons.

Q3. How will Alzheimer's affect our lives?

R3. In the early stages of the disease, our loved ones may have trouble taking care of themselves, cooking, shopping, paying bills, and learning new things (how to use a cell phone or modern home appliance). Patients may have increasing orientation and memory problems in the more advanced stages, get lost in familiar places, or may no longer recognize close people, sometimes even their children or life partners. In the most advanced stages, there are serious problems of motor coordination, the inability to hug, to move, there are problems of balance, and frequent falls with major risks of serious fractures (fractures of the upper limbs, fracture of the femoral neck, skull fractures, etc). There may also be moments of psycho-motor agitation with physical aggression,

Q4. Is the ability to drive cars affected?

4. Unfortunately, this disease involves impaired coordination, reflexes, memory, the ability to orient, which are strictly necessary at the wheel. If you see these signs and fail to persuade the patient to stop driving, seek medical attention. The social risks involved in these cases are considerable. In more severe cases, when patients refuse to comply with family or medical instructions, an official reassessment of driving ability or driver's license may be requested.

Q5. Are exercises useful?

5. Everyone knows that a normal life should contain as much exercise as possible, and Alzheimer's patients are no exception. Recent studies have shown the usefulness of physical activity in combating cognitive impairment. Involvement in group sports activities, adapted to the medical condition, is even more useful, providing the patient's necessary social gear.

Q6.  What are the role of family and loved ones?

6. If you are in the situation of caring for a patient who has Alzheimer's dementia, you must be very well informed about the evolution and particularities of this disease. It will be a big responsibility on your shoulders, and it will take much effort. You will have to deal with both the patient's manifestations and your reactions to the stress you will be subjected to. Often, the informed decision-making capacity of Alzheimer's patients deteriorates rapidly, and you have to fill that role by establishing guardianship in court. You will also have to struggle to give the patient "on the tray" everything he needs without asking him to get involved in any activity, which will lead to hastening and increasing his dependence on you.

Q7. What are the challenges for those who care for a person with Alzheimer's?

7. If in the early stages of the disease patients know and understand what is happening to them, as it progresses, extremely disturbing situations may arise. Patients can become suspicious, paranoid, even violent, they can accuse you of all sorts of things - that you steal their money, that you poison them, that you keep them locked up, they can try to "escape". In all these cases, you should seek the help of a psychiatrist.   

Q8. How do we manage the advanced stages of the disease?

8. In the more advanced stages of the disease, problems may require institutionalization of the patient in a specialized medically assisted care unit, where patients are supervised and cared for by qualified personnel. You have to keep in mind that often in these phases, patients no longer recognize their closest relatives and raise major problems due to sphincter incontinence, balance problems, maintenance of hygiene, or swallowing problems. It indicates the hospitalization of patients in-hospital palliative care departments to ensure adequate physical and mental comfort.

If you have any regular mental illness and want the treatment, join the recovery groups in Louisville, Kentucky.

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